Millipore Sigma Vibrant Logo

567737 S1P4 Receptor Antagonist, CYM50358 - CAS 1314212-39-9 - Calbiochem

The S1P4 Receptor Antagonist, CYM50358 controls the biological activity of S1P4 Receptor. This small molecule/inhibitor is primarily used for Biochemicals applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: CYM50358

View Products on Sigmaaldrich.com
567737
View Pricing & Availability

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
1314212-39-9C₂₀H₁₈Cl₂N₂O₂

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
567737-5MG
Retrieving availability...
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      		 Glass bottle 5 mg
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      —
      Request Pricing
      		 —
      Description
      OverviewAn arylcarboxamide that acts as a potent and selective sphingosine-1-phosphate receptor 4 (S1P4) antagonist (IC50 = 25 nM), among a panel of five S1P receptors. It is shown to inhibit other S1P isoforms only at much higher concentrations (IC50 = 6.4 µM, 3.9 µM, 5.5 µM, and 25 µM for S1P1, S1P2, S1P5, and S1P3 (95% inhibition), respectively).
      Catalogue Number567737
      Brand Family Calbiochem®
      SynonymsCYM50358
      References
      ReferencesGuerrero, M., et al. 2011. Bioorg. Med. Chem. Lett. 21, 3632.
      Product Information
      CAS number1314212-39-9
      FormWhite solid
      Hill FormulaC₂₀H₁₈Cl₂N₂O₂
      Chemical formulaC₂₀H₁₈Cl₂N₂O₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Regulatory Review
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      567737-5MG 04055977190915

      Documentation

      S1P4 Receptor Antagonist, CYM50358 - CAS 1314212-39-9 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      S1P4 Receptor Antagonist, CYM50358 - CAS 1314212-39-9 - Calbiochem Certificates of Analysis

      TitleLot Number
      567737

      References

      Reference overview
      Guerrero, M., et al. 2011. Bioorg. Med. Chem. Lett. 21, 3632.

      Brochure

      Title
      New Products: Volume 3, 2012
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision30-April-2012 JSW
      SynonymsCYM50358
      DescriptionAn arylcarboxamide that acts as a potent and selective sphingosine-1-phosphate receptor 4 (S1P4) antagonist (IC50 = 25 nM), among a panel of five S1P receptors. It is shown to inhibit other S1P isoforms only at much higher concentrations (IC50 = 6.4 µM, 3.9 µM, 5.5 µM, and 25 µM for S1P1, S1P2, S1P5, and S1P3 (95% inhibition), respectively).
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number1314212-39-9
      Chemical formulaC₂₀H₁₈Cl₂N₂O₂
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (100 mg/ml; clear, colorless solution)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Regulatory Review
      ReferencesGuerrero, M., et al. 2011. Bioorg. Med. Chem. Lett. 21, 3632.