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551826 QUIN 2, Tetrapotassium Salt - CAS 73630-23-6 - Calbiochem

Binding of Ca2+ leads to a major shift in UV absorption spectrum and a twenty-fold enhancement in fluorescence quantum yield.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-{[2-bis(Carboxymethyl)amino-5-methylphenoxy]methyl}-6-methoxy-8-bis(carboxymethyl)aminoquinoline, 4K

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551826
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
73630-23-6C₂₆H₂₃N₃O₁₀ · 4K

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551826-50MG
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      		 Plastic ampoule 50 mg
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      Description
      OverviewBinding of Ca2+ leads to a major shift in UV absorption spectrum and a twenty-fold enhancement in fluorescence quantum yield. TPEN (Cat. No. 616394) can be used in conjunction with QUIN 2 to reduce heavy-metal quenching of QUIN 2 fluorescence in cells.
      Catalogue Number551826
      Brand Family Calbiochem®
      Synonyms2-{[2-bis(Carboxymethyl)amino-5-methylphenoxy]methyl}-6-methoxy-8-bis(carboxymethyl)aminoquinoline, 4K
      References
      ReferencesKomada, H., et al. 1989. Cell Struct. Funct. 14, 141.
      Vijayaraghavan, S. and Hoskins, D. 1989. Cell Calcium 10, 241.
      Arslan, P., et al. 1985. J. Biol. Chem. 260, 2719.
      Bryant, D.T. 1985. Biochem. J. 226, 613.
      Grynkiewicz, G., et al. 1985. J. Biol. Chem. 260, 3440.
      Ashley R.H., et al. 1984. Biochem. J. 219, 149.
      Tsien, R.Y., et al. 1982. J. Cell Biol. 94, 325.
      Tsien, R.Y. 1980. Biochemistry 19, 2396.
      Product Information
      CAS number73630-23-6
      ATP CompetitiveN
      FormYellow solid
      Hill FormulaC₂₆H₂₃N₃O₁₀ · 4K
      Chemical formulaC₂₆H₂₃N₃O₁₀ · 4K
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetCalcium Probes
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Emission max.
      Excitation max.
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) under an inert gas, pH >10. Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      551826-50MG 04055977268270

      Documentation

      QUIN 2, Tetrapotassium Salt - CAS 73630-23-6 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      QUIN 2, Tetrapotassium Salt - CAS 73630-23-6 - Calbiochem Certificates of Analysis

      TitleLot Number
      551826

      References

      Reference overview
      Komada, H., et al. 1989. Cell Struct. Funct. 14, 141.
      Vijayaraghavan, S. and Hoskins, D. 1989. Cell Calcium 10, 241.
      Arslan, P., et al. 1985. J. Biol. Chem. 260, 2719.
      Bryant, D.T. 1985. Biochem. J. 226, 613.
      Grynkiewicz, G., et al. 1985. J. Biol. Chem. 260, 3440.
      Ashley R.H., et al. 1984. Biochem. J. 219, 149.
      Tsien, R.Y., et al. 1982. J. Cell Biol. 94, 325.
      Tsien, R.Y. 1980. Biochemistry 19, 2396.

      Brochure

      Title
      Fluorescent Calcium Probes Technical Bulletin
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-July-2010 JSW
      Synonyms2-{[2-bis(Carboxymethyl)amino-5-methylphenoxy]methyl}-6-methoxy-8-bis(carboxymethyl)aminoquinoline, 4K
      DescriptionBinding of Ca2+ to QUIN 2 leads to a major shift in UV absorption spectrum and a twenty-fold enhancement in fluorescence quantum yield. TPEN (Cat. No. 616394) can be used in conjunction with QUIN 2 to reduce heavy-metal quenching of QUIN 2 fluorescence in cells. Spectral properties in the presence of low calcium concentrations (ex. 354 nm, em. 510 nm) differ from those during high calcium conditions (ex. 332 nm, em. 505 nm).
      FormYellow solid
      CAS number73630-23-6
      Chemical formulaC₂₆H₂₃N₃O₁₀ · 4K
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityH₂O (10 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) under an inert gas, pH >10. Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Irritant
      ReferencesKomada, H., et al. 1989. Cell Struct. Funct. 14, 141.
      Vijayaraghavan, S. and Hoskins, D. 1989. Cell Calcium 10, 241.
      Arslan, P., et al. 1985. J. Biol. Chem. 260, 2719.
      Bryant, D.T. 1985. Biochem. J. 226, 613.
      Grynkiewicz, G., et al. 1985. J. Biol. Chem. 260, 3440.
      Ashley R.H., et al. 1984. Biochem. J. 219, 149.
      Tsien, R.Y., et al. 1982. J. Cell Biol. 94, 325.
      Tsien, R.Y. 1980. Biochemistry 19, 2396.