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437622 Lipocortin-II, His•Tag®, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Annexin-II, Human, Recombinant, Calpactin-I, Human, Recombinant, Lipocortin-II, Human, Recombinant

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437622
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.



      Full-length, recombinant, human, lipocortin-II fused at the N-terminus to His•Tag® and S•Tag™ sequences and expressed in E. coli. This preparation is qualified for use as a substrate for protein tyrosine kinases in in vitro assays. Lipocortin-II is a Ca2+-binding protein whose affinity for calcium is increased by anionic phospholipids. It binds two calcium ions with high-affinity and crosslinks plasma membrane phospholipids with actin and the cytoskeleton and is involved with exocytosis. It is known to be phosphorylated at Tyr23 by Src and at Ser25 by PKC. It is also a substrate for a variety of other protein tyrosine kinases.
      Catalogue Number437622
      Brand Family Calbiochem®
      SynonymsAnnexin-II, Human, Recombinant, Calpactin-I, Human, Recombinant, Lipocortin-II, Human, Recombinant
      Application Data
      References
      ReferencesDeora, A.B., et al. 2004. J. Biol. Chem. 279, 43411.
      Lennon, G., et al. 1996. Genomics 33, 151.
      Barton, G. J., et al. 1991. Eur. J. Biochem. 198, 749.
      Product Information
      FormLiquid
      FormulationIn PBS, 0.2% Protease Inhibitor Cocktail Set VII (Cat. No. 539138).
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥90% by SDS-PAGE
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Irritant
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      437622 0

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      Lipocortin-II, His•Tag®, Human, Recombinant, E. coli SDS

      Title

      Safety Data Sheet (SDS) 

      Lipocortin-II, His•Tag®, Human, Recombinant, E. coli Certificates of Analysis

      TitleLot Number
      437622

      References

      Reference overview
      Deora, A.B., et al. 2004. J. Biol. Chem. 279, 43411.
      Lennon, G., et al. 1996. Genomics 33, 151.
      Barton, G. J., et al. 1991. Eur. J. Biochem. 198, 749.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-August-2008 RFH
      SynonymsAnnexin-II, Human, Recombinant, Calpactin-I, Human, Recombinant, Lipocortin-II, Human, Recombinant
      Application Data
      DescriptionFull-length, recombinant, human, lipocortin-II fused at the N-terminus to His•Tag® and S•Tag™ sequences and expressed in E. coli. This preparation is qualified for use as a substrate for protein tyrosine kinases in in vitro assays. Lipocortin-II is a Ca2+-binding protein whose affinity for calcium is increased by anionic phospholipids. It binds two calcium ions with high-affinity and crosslinks plasma membrane phospholipids with actin and the cytoskeleton and is involved with exocytosis. It is known to be phosphorylated at Tyr23 by Src and at Ser25 by PKC. It is also a substrate for a variety of other protein tyrosine kinases.
      FormLiquid
      FormulationIn PBS, 0.2% Protease Inhibitor Cocktail Set VII (Cat. No. 539138).
      Concentration Label Please refer to vial label for lot-specific concentration
      Purity≥90% by SDS-PAGE
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Irritant
      ReferencesDeora, A.B., et al. 2004. J. Biol. Chem. 279, 43411.
      Lennon, G., et al. 1996. Genomics 33, 151.
      Barton, G. J., et al. 1991. Eur. J. Biochem. 198, 749.