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407318 β-Interferon, Human, Recombinant, CHO Cells

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407318
  
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      Overview

      Description
      Overview

      This product has been discontinued.



      Recombinant, human interferon-β (IFN-β) expressed in CHO cells as a single glycosylated polypeptide containing 166 amino acids. Purified by chromatographic methods. IFN-β is a type I cytokine produced in response to exposure to viruses or double-stranded RNAs. It is also induced by other cytokines, such as TNF and IL-1. It is involved in the regulation of non-specific humoral immune responses and immune responses to viral infections, and thus exhibits anti-viral, anti-proliferative, and immunomodulating properties. The biological activity of IFN-β, unlike IFN-α, is strictly species-specific and will not be active across species.

      Catalogue Number407318
      Brand Family Calbiochem®
      SynonymsInterferon α-2 precursor, IFN-β-1a, rHuIFN-β-1a
      References
      ReferencesGoebel, M.U., et al. 2005. Physiol. Behav. 84, 807.
      Graber, J., et al. 2005. J. Neuroimmunol. 161,169.
      Mallada-Frechin, J., et al. 2005. Rev. Neurol. 40, 482.
      Patten, S.B., et al. 2005. Mult. Scler. 11, 175.
      Pohl, D., et al. 2005. Neurology 64, 888.
      Schwid, S.R., et al. 2005. Arch. Neurol. 62, 785.
      Product Information
      FormLyophilized
      FormulationLyophilized from 62 mg/ml mannitol, 9.1 mg/ml human albumin, 0.9 mg/ml acetate, pH 7.0-7.2.
      Quality LevelMQ100
      Biological Information
      Biological activityReported as IU/mg on a lot-specific basis using a viral resistance assay
      Purity≥98% by SDS-PAGE
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 7 days at 4°C or for up to 4 months at -20°C. Avoid freeze/thaw cycles of solutions.
      Global Trade Item Number
      Catalogue Number GTIN
      407318 0