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345670
Sigma-AldrichGalanthamine, Hydrobromide - CAS 69353-21-5 - Calbiochem
A competitive and reversible inhibitor of acetylcholinesterase.
More>>A competitive and reversible inhibitor of acetylcholinesterase. Less<<
MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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Description
Overview
A competitive and reversible inhibitor of acetylcholinesterase. Antimyasthenic agent. Can partially reverse the effects of scopolamine-induced amnesia in rats. Reported to improve learning and short-term memory in animal models.
Catalogue Number
345670
Brand Family
Calbiochem®
Synonyms
Nivalin, HBr
References
References
Pilger, C., et al. 2001. J. Mol. Graph. Model19, 288. Iliev, A., et al. 1999. Methods Find. Exp. Clin. Pharmacol. 21, 297. Southan, G.J., et al. 1996. Br. J. Pharmacol.117, 619. Mutafova-Yambolieva, V.N., et al. 1993. Gen. Pharmacol. 24, 1253.
Do not breathe dust. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code
Ambient Temperature Only
Toxicity
Toxic
Hazardous Materials Attention:
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage
+2°C to +8°C
Protect from Moisture
Protect from moisture
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Galanthamine, Hydrobromide - CAS 69353-21-5 - Calbiochem Certificates of Analysis
Title
Lot Number
345670
References
Reference overview
Pilger, C., et al. 2001. J. Mol. Graph. Model19, 288. Iliev, A., et al. 1999. Methods Find. Exp. Clin. Pharmacol. 21, 297. Southan, G.J., et al. 1996. Br. J. Pharmacol.117, 619. Mutafova-Yambolieva, V.N., et al. 1993. Gen. Pharmacol. 24, 1253.
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
30-March-2010 RFH
Synonyms
Nivalin, HBr
Description
Cholinesterase antagonist. Antimyasthenic agent. Can partially reverse the effects of scopolamine-induced amnesia in rats.
Form
White solid
CAS number
69353-21-5
RTECS
DF8075000
Chemical formula
C₁₇H₂₁NO₃ · HBr
Structure formula
Purity
≥95% by HPLC
Solubility
DMSO (5 mg/ml), Ethanol (1 mg/ml) or H₂O (1 mg/ml)
Storage
Protect from moisture +2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Toxic
Merck USA index
14, 4340
References
Pilger, C., et al. 2001. J. Mol. Graph. Model19, 288. Iliev, A., et al. 1999. Methods Find. Exp. Clin. Pharmacol. 21, 297. Southan, G.J., et al. 1996. Br. J. Pharmacol.117, 619. Mutafova-Yambolieva, V.N., et al. 1993. Gen. Pharmacol. 24, 1253.
