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341492 FeTPPS - Calbiochem

Overview

Replacement Information

Key Spec Table

Empirical Formula
C₄₄H₂₈ClFeN₄O₁₂S₄

Pricing & Availability

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341492-25MG
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      Plastic ampoule 25 mg
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      Description
      OverviewA ferric porphyrin complex that catalytically isomerizes peroxynitrite to nitrate both in vivo and in vitro. Hence, serves as a selective peroxynitrite scavenger and decomposition catalyst. Provides cytoprotection against peroxynitrite (EC50 = 5 µM). Does not complex with nitric oxide and exhibits minimal SOD mimetic activity.
      Catalogue Number341492
      Brand Family Calbiochem®
      Synonyms5,10,15,20-Tetrakis(4-sulfonatophenyl)porphyrinato Iron (III), Chloride
      References
      ReferencesImam, S.Z., et al. 2000. Ann. N.Y. Acad. Sci. 914, 157.
      Misko, T.P., et al. 1998. J. Biol. Chem. 273, 15646.
      Product Information
      ATP CompetitiveN
      FormDark brown solid
      Hill FormulaC₄₄H₂₈ClFeN₄O₁₂S₄
      Chemical formulaC₄₄H₂₈ClFeN₄O₁₂S₄
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetSelective peroxynitrite scavenger
      Primary Target IC<sub>50</sub>EC50 = 5 µM for cytoprotection against peroxynitrite
      Purity≥95% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 weeks at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      341492-25MG 04055977215694

      Documentation

      FeTPPS - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      FeTPPS - Calbiochem Certificates of Analysis

      TitleLot Number
      341492

      References

      Reference overview
      Imam, S.Z., et al. 2000. Ann. N.Y. Acad. Sci. 914, 157.
      Misko, T.P., et al. 1998. J. Biol. Chem. 273, 15646.

      Brochure

      Title
      Pathways and Biomarkers of Oxidative Stress
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision24-June-2008 RFH
      Synonyms5,10,15,20-Tetrakis(4-sulfonatophenyl)porphyrinato Iron (III), Chloride
      DescriptionA ferric porphyrin complex that catalytically isomerizes peroxynitrite to nitrate both in vivo and in vitro. Provides cytoprotection against peroxynitrite (EC50 = 5 µM). Does not complex with nitric oxide and exhibits minimal SOD mimetic activity.
      FormDark brown solid
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₄₄H₂₈ClFeN₄O₁₂S₄
      Structure formulaStructure formula
      Purity≥95% by TLC
      SolubilityH₂O
      Storage Protect from light
      +2°C to +8°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 weeks at -20°C.
      Toxicity Standard Handling
      ReferencesImam, S.Z., et al. 2000. Ann. N.Y. Acad. Sci. 914, 157.
      Misko, T.P., et al. 1998. J. Biol. Chem. 273, 15646.