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341273 Factor D, Human

Factor D, Human, is a native single-chain glycoprotein with serine protease activity. Cleaves, and thus activates, Factor B during activation of complement via the alternative pathway.

Factor D, Human MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: C3 Activator Convertase, Adipsin

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341273
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Overview

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341273-25UG
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      		 Plastic ampoule 25 μg
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      Description
      OverviewNative factor D from human serum. Single-chain glycoprotein composed of 222 amino acids, present in normal human serum at about 1.4 µg/ml. Serine protease that cleaves, and thus activates, Factor B during activation of complement via the alternative pathway. Has recently been shown to be identical to adipsin, a serine protease secreted into the bloodstream by adipocytes.
      Catalogue Number341273
      Brand Family Calbiochem®
      SynonymsC3 Activator Convertase, Adipsin
      References
      ReferencesJing, H., et al. 1999. EMBO J. 18, 804.
      Volankis, J.E., et al. 1985. N. Engl. J. Med. 312, 395.
      Niemann, M.A., et al. 1984. J. Immunol. 132, 809.
      Product Information
      FormLiquid
      FormulationIn PBS, pH 7.2.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityIgG, IgA, IgM, Factor H, Factor B, or albumin: ≤trace amounts
      Purity≥90% by SDS-PAGE
      SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      341273-25UG 04055977215557

      Documentation

      Factor D, Human SDS

      Title

      Safety Data Sheet (SDS) 

      Factor D, Human Certificates of Analysis

      TitleLot Number
      341273

      References

      Reference overview
      Jing, H., et al. 1999. EMBO J. 18, 804.
      Volankis, J.E., et al. 1985. N. Engl. J. Med. 312, 395.
      Niemann, M.A., et al. 1984. J. Immunol. 132, 809.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision24-June-2008 RFH
      SynonymsC3 Activator Convertase, Adipsin
      DescriptionNative factor D from human serum. Single-chain glycoprotein composed of 222 amino acids present in normal human serum at about 1.4 µg/ml. Serine protease that cleaves, and thus activates, Factor B during activation of complement via the alternative pathway. Has recently been shown to be identical to adipsin, a serine protease secreted into the bloodstream by adipocytes.
      FormLiquid
      FormulationIn PBS, pH 7.2.
      SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Purity≥90% by SDS-PAGE
      Biological activityIgG, IgA, IgM, Factor H, Factor B, or albumin: ≤trace amounts
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesJing, H., et al. 1999. EMBO J. 18, 804.
      Volankis, J.E., et al. 1985. N. Engl. J. Med. 312, 395.
      Niemann, M.A., et al. 1984. J. Immunol. 132, 809.