218761 Sigma-AldrichCaspase-9 Inhibitor I - Calbiochem
Caspase-9 Inhibitor I, CAS 210345-04-3, is a potent, cell-permeable, and irreversible inhibitor of caspase-9.
More>> Caspase-9 Inhibitor I, CAS 210345-04-3, is a potent, cell-permeable, and irreversible inhibitor of caspase-9. Less<<Caspase-9 Inhibitor I - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Z-LE(OMe)HD(OMe)-FMK
Recommended Products
Overview
Key Spec Table
| Empirical Formula |
|---|
| C₃₂H₄₃FN₆O₁₀ |
| Description | |
|---|---|
| Overview | This product has been discontinued. A potent, cell-permeable, and irreversible inhibitor of caspase-9. May also inhibit caspase-4 and caspase-5. When using with purified native or recombinant enzyme, pretreatment with an esterase is required. A 5 mM (250 µg/72 µl) solution of Z-LEHD-FMK (Cat. No. 218841) in DMSO is also available. |
| Catalogue Number | 218761 |
| Brand Family | Calbiochem® |
| Synonyms | Z-LE(OMe)HD(OMe)-FMK |
| References | |
|---|---|
| References | Fadeel, B., et al. 1999. Leukemia 13, 719. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Form | White to light brown solid |
| Formulation | Supplied as a trifluoroacetate salt. |
| Hill Formula | C₃₂H₄₃FN₆O₁₀ |
| Chemical formula | C₃₂H₄₃FN₆O₁₀ |
| Reversible | N |
| Quality Level | MQ100 |
| Applications | |
|---|---|
| Application | Caspase-9 Inhibitor I, CAS 210345-04-3, is a potent, cell-permeable, and irreversible inhibitor of caspase-9. |
| Biological Information | |
|---|---|
| Primary Target | caspase-4, caspase-5, caspase-9 |
| Purity | single spot by TLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | Y |
| Peptide Sequence | Z-Leu-Glu(OMe)-His-Asp(OMe)-CH₂F* |
| Global Trade Item Number | |
|---|---|
| Catalogue Number | GTIN |
| 218761 | 0 |