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218739 Caspase-1 Substrate X, Fluorogenic - CAS 189275-74-9 - Calbiochem

A fluorogenic substrate for detecting caspase-1 (ICE), caspase-4, and caspase-5 activity.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Caspase-5 Substrate III, Fluorogenic, Ac-WEHD-AMC

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218739
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218739-5MG
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      Description
      OverviewA fluorogenic substrate for detecting caspase-1 (ICE), caspase-4, and caspase-5 activity.
      Catalogue Number218739
      Brand Family Calbiochem®
      SynonymsCaspase-5 Substrate III, Fluorogenic, Ac-WEHD-AMC
      References
      ReferencesThornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.
      Product Information
      CAS number189275-74-9
      ATP CompetitiveN
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₃₈H₄₀N₈O₁₁
      Chemical formulaC₃₈H₄₀N₈O₁₁
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetA fluorogenic substrate for detecting caspase-1 (ICE), caspase-4, and caspase-5 activity.
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Emission max.
      Excitation max.
      Peptide SequenceAc-Trp-Glu-His-Asp-AMC
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      218739-5MG 04055977218985

      Documentation

      Caspase-1 Substrate X, Fluorogenic - CAS 189275-74-9 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Caspase-1 Substrate X, Fluorogenic - CAS 189275-74-9 - Calbiochem Certificates of Analysis

      TitleLot Number
      218739

      References

      Reference overview
      Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.

      Brochure

      Title
      Caspases and other Apoptosis Related Tools Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-June-2008 RFH
      SynonymsCaspase-5 Substrate III, Fluorogenic, Ac-WEHD-AMC
      DescriptionA fluorogenic substrate for detecting caspase-1 (ICE) (excitation maximum: ~365-380 nm; emission maximum: ~430-460 nm).
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      CAS number189275-74-9
      Chemical formulaC₃₈H₄₀N₈O₁₁
      Peptide SequenceAc-Trp-Glu-His-Asp-AMC
      Purity≥95% by HPLC
      SolubilityDMSO (5 mg/ml)
      Storage Protect from moisture
      Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesThornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.