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203639 BMP-4, Mouse, Recombinant

BMP-4, Mouse, Recombinant MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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203639
  
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      Overview

      Replacement Information

      Key Spec Table

      Purity
      ≥95% by SDS-PAGE
      Description
      Overview

      This product has been discontinued.



      Recombinant, mouse BMP-4 consisting of amino acids 293-408 and expressed in Chinese Hamster Ovary cells. BMP-4 plays a key role in epidermal determination, the development of multiple organs, suppression of neural induction, tissue repair, and mesenchyme formation.
      Catalogue Number203639
      Brand Family Calbiochem®
      References
      ReferencesLavery, K., et al. 2008. J. Biol. Chem. April 24 epub.
      Zhang, P., et al. 2008. Blood 111, 1933.
      Gambaro, K., et al. 2006. Cell Death Differ. 13, 1075.
      Rosen, V., 2006. Ann. N.Y. Acad. Sci. 1068, 19.
      Frank, D.B., et al. 2005. Circ. Res. 97, 496.
      Simic, P. and S. Vukicevic. 2005. Cytokine Growth Factor Rev. 16, 299.
      Chen, D., et al. 2004. Growth Factors 22, 233.
      Sadlon, T.J., et al. 2004. Stem Cells 22 457.
      Takada, T., et al. 2003. J. Biol. Chem. 278 43229.
      Cui, Y., et al. 2001. Genes Dev. 15, 2797.
      Cui, Y., et al. 1998. EMBO J. 17, 4735.
      Jones, C.M. and J.C. Smith. 1998. Dev. Biol. 194, 12.
      Nishimatsu, S. and G.H. Thomsen. 1998. Mech. Dev. 74 75.
      Aono, A. et al. 1995. Biochem. Biophys. Res. Commun. 210, 670.
      Oida, S., et al. 1995. DNA Seq. 5, 273.
      Product Information
      FormLiquid
      FormulationLyophilized from 0.2 µm sterile-filtered Acetonitrile, TFA, BSA.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityED₅₀ = 10-40 ng/ml as measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells.
      Purity≥95% by SDS-PAGE
      Physicochemical Information
      ContaminantsEndotoxin: <1.0 EU/µg protein
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      203639 0

      Documentation

      BMP-4, Mouse, Recombinant SDS

      Title

      Safety Data Sheet (SDS) 

      BMP-4, Mouse, Recombinant Certificates of Analysis

      TitleLot Number
      203639

      References

      Reference overview
      Lavery, K., et al. 2008. J. Biol. Chem. April 24 epub.
      Zhang, P., et al. 2008. Blood 111, 1933.
      Gambaro, K., et al. 2006. Cell Death Differ. 13, 1075.
      Rosen, V., 2006. Ann. N.Y. Acad. Sci. 1068, 19.
      Frank, D.B., et al. 2005. Circ. Res. 97, 496.
      Simic, P. and S. Vukicevic. 2005. Cytokine Growth Factor Rev. 16, 299.
      Chen, D., et al. 2004. Growth Factors 22, 233.
      Sadlon, T.J., et al. 2004. Stem Cells 22 457.
      Takada, T., et al. 2003. J. Biol. Chem. 278 43229.
      Cui, Y., et al. 2001. Genes Dev. 15, 2797.
      Cui, Y., et al. 1998. EMBO J. 17, 4735.
      Jones, C.M. and J.C. Smith. 1998. Dev. Biol. 194, 12.
      Nishimatsu, S. and G.H. Thomsen. 1998. Mech. Dev. 74 75.
      Aono, A. et al. 1995. Biochem. Biophys. Res. Commun. 210, 670.
      Oida, S., et al. 1995. DNA Seq. 5, 273.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision20-Sepmtember-2011 RFH
      DescriptionRecombinant, mouse BMP-4 consisting of amino acids 293-408 and expressed in Chinese Hamster Ovary cells. BMP-4 plays a key role in epidermal determination, the development of multiple organs, suppression of neural induction, tissue repair, and mesenchyme formation.
      FormLiquid
      FormulationLyophilized from 0.2 µm sterile-filtered Acetonitrile, TFA, BSA.
      Purity≥95% by SDS-PAGE
      ContaminantsEndotoxin: <1.0 EU/µg protein
      Biological activityED₅₀ = 10-40 ng/ml as measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells.
      SolubilityReconstitute to 100 µg/ml in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin.
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesLavery, K., et al. 2008. J. Biol. Chem. April 24 epub.
      Zhang, P., et al. 2008. Blood 111, 1933.
      Gambaro, K., et al. 2006. Cell Death Differ. 13, 1075.
      Rosen, V., 2006. Ann. N.Y. Acad. Sci. 1068, 19.
      Frank, D.B., et al. 2005. Circ. Res. 97, 496.
      Simic, P. and S. Vukicevic. 2005. Cytokine Growth Factor Rev. 16, 299.
      Chen, D., et al. 2004. Growth Factors 22, 233.
      Sadlon, T.J., et al. 2004. Stem Cells 22 457.
      Takada, T., et al. 2003. J. Biol. Chem. 278 43229.
      Cui, Y., et al. 2001. Genes Dev. 15, 2797.
      Cui, Y., et al. 1998. EMBO J. 17, 4735.
      Jones, C.M. and J.C. Smith. 1998. Dev. Biol. 194, 12.
      Nishimatsu, S. and G.H. Thomsen. 1998. Mech. Dev. 74 75.
      Aono, A. et al. 1995. Biochem. Biophys. Res. Commun. 210, 670.
      Oida, S., et al. 1995. DNA Seq. 5, 273.