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100129 L-Aspartic acid

EMPROVE® EXPERT Ph Eur,BP,ChP,JP,USP

L-Aspartic acid MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: L-a-Aminosuccinic acid, L-αlpha-Aminosuccinic acid, Asp

CAS #: 56-84-8 EC Number: 200-291-6 Molar Mass: 133.10 g/mol Hill Formula: C₄H₇NO₄ Grade: Ph Eur,BP,ChP,JP,USP
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100129
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Overview

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
56-84-8200-291-6C₄H₇NO₄133.10 g/molPh Eur,BP,ChP,JP,USP

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          Description
          Catalogue Number100129
          SynonymsL-a-Aminosuccinic acid, L-αlpha-Aminosuccinic acid, Asp
          Product Information
          CAS number56-84-8
          EC number200-291-6
          GradePh Eur,BP,ChP,JP,USP
          Hill FormulaC₄H₇NO₄
          Molar Mass133.10 g/mol
          HS Code2922 49 85
          Structure formula ImageStructure formula Image
          Quality LevelMQ500
          Physicochemical Information
          Density1.66 g/cm3 (13 °C)
          Melting Point230 °C (decomposition)
          pH value3.03 (10 g/l, H₂O)
          Bulk density430 kg/m3
          Solubility4 g/l
          Safety Information according to GHS
          Storage class10 - 13 Other liquids and solids
          WGKWGK 1 slightly hazardous to water
          Disposal3
          Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
          Storage and Shipping Information
          StorageStore at +2°C to +30°C.
          Specifications
          Assay (alkalimetric, calculated on dried substance)98.5 - 101.0 %
          Identity (IR-spectrum)passes test
          Identity (enantiomeric purity)passes test
          Identity (TLC)passes test
          Appearancewhite to almost white, crystalline powder or colorless crystals
          Appearance of solution (50 g/l; hydrochloric acid 1 mol/l)clear and not more intense in color than reference solution BY₆
          Transmittance of solution (100 g/l, hydrochloric acid 1 mol/l)≥ 98.0 %
          Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+24.0 to +26.0
          pH (4 g/l CO2-free water)2.5 - 3.5
          Acidity (5 g/l, water)2.0 - 4.0
          Chloride (Cl)≤ 200 ppm
          Sulfate (SO₄)≤ 200 ppm
          Heavy metals (as Pb)≤ 10 ppm
          Iron (Fe)≤ 10 ppm
          As (Arsenic)≤ 1 ppm
          Enantiomeric purity (HPLC) (D-aspartic acid)≤ 0.3 %
          Dicarboxylic acids (HPLC) (malic acid)≤ 0.2 %
          Dicarboxylic acids (HPLC) (fumaric acid)≤ 0.10 %
          Dicarboxylic acids (HPLC) (maleic acid)≤ 0.10 %
          Dicarboxylic acids (HPLC) (any unspecified impurity)≤ 0.10 %
          Dicarboxylic acids (HPLC) (total unspecified impurities)≤ 0.3 %
          Related compounds (HPLC) (maleic acid)≤ 0.05 %
          Related compounds (HPLC) (malic acid)≤ 0.20 %
          Related compounds (HPLC) (fumaric acid)≤ 0.10 %
          Related compounds (HPLC) (Any unspecified impurity)≤ 0.05 %
          Related compounds (HPLC) (Total unspecified impurities)≤ 0.10 %
          Ninhydrin-positive substances (LC)(impurity C (glutamic acid))≤ 0.2 %
          Ninhydrin-positive substances (LC)(impurity D (alanine))≤ 0.2 %
          Ninhydrin-positive substances (LC)(impurity G (asparagine))≤ 0.2 %
          Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.10 %
          Ninhydrin-positive substances (LC) (total impurities)≤ 1.0 %
          Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
          Other amino acids (TLC)≤ 0.5 %
          Related substances (TLC)passes test
          Residual solvents (ICH Q3C)excluded by manufacturing process
          Sulfated ash (600 °C)≤ 0.1 %
          Loss on drying (105 °C; 3 h)≤ 0.20 %
          Bacterial endotoxins≤ 25 I.U./g
          Microbiological test (total aerobic microbial count (TAMC))≤ 10²
          Microbiological test (total yeast and mould count (TYMC))≤ 10²
          Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
          Compliance with pyrogens (according to ChP) is guaranteed by the test for bacterial endotoxins (ChP) and the production process.
          Corresponds to Ph. Eur., BP, ChP, JP, USP.
          Global Trade Item Number
          Catalogue Number GTIN
          1001291000 04022536002194
          1001299025 04022536725109