Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
-MAPmates™ that require a different assay buffer
-Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
-PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701)
-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
-GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
.
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Select A Species, Panel Type, Kit or Sample Type
To begin designing your MILLIPLEX® MAP kit select a species, a panel type or kit of interest.
Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
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96-Well Plate
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Add Additional Reagents (Buffer and Detection Kit is required for use with MAPmates)
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48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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BDNF is a important neurotrophic factor essential for proper neuronal development and survival of various neuronal populations in the CNS and PNS. BDNF is also key for axonal growth and path finding of dendritic growth and morphology. BDNF also is key to neuronal responses and LTP or LTD and synaptic plasticity, behavior, learning and memory. BDNF is also important in neuronal disease and is being studied as potential marker in various diseases. Finally, BDNF is expressed initially as a proform protein long thought to simply be an inactive proform factor, however recent research demonstrates that proBDNF may play roles not only in neuronal development but also development in general as well as in adult metabolism in brain, muscle, and general metabolic function, so the research into BDNF is growing. BDNF is expressed developmentally in the brain and developing nervous system but it is also expressed in the adult in the brain, gut, muscle, lung, testis, prostate and placenta.
References
Product Information
Format
Purified
HS Code
3002 15 90
Presentation
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
~25 kDa observed. UnitProt describes 5 isoforms produced by alternative promoter usage and alternative splicing ranging from 27.8 to 37.1 kDa.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in mouse brain membrane tissue lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected BDNF in 10 µg of mouse brain membrane tissue lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Stable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size
200 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number
GTIN
MABN79
04055977136296
Documentation
Anti-BDNF Antibody, clone 8G8.2 Certificates of Analysis
