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MABF290 Anti-S100A9 Antibody, clone 2A5 (Azide Free)

Anti-S100A9 Antibody, clone 2A5 (Azide Free) is an antibody against S100A9 for use in western blotting & activity assay.

Anti-S100A9 Antibody, clone 2A5 (Azide Free) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunological Signaling Gene Symbol: S100a9, Cagb, Mrp14 UniProt Number: P31725
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MABF290
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWB, ACTRPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABF290
      DescriptionAnti-S100A9 Antibody, clone 2A5 (Azide Free)
      Alternate Names
      • Protein S100-A9
      • Calgranulin-B
      • Leukocyte L1 complex heavy chain
      • Migration inhibitory factor-related protein 14
      • MRP-14
      • p14
      • S100 calcium-binding protein A9
      Background InformationS100A9, also known as Calgranulin-B, Leukocyte L1 complex heavy chain, Migration inhibitory factor-related protein 14, MRP-14, p14, or S100 calcium-binding protein A9, and encoded by the gene S100A9/CAGB/MRP14/S100-A9 is a calcium and zinc binding protein that plays a prominent role in the regulation of inflammatory processes and immune responses. S100-A9 can induce neutrophil chemotaxis and adhesion. S100-A9 one of the subunits of Calprotectin, which is a complex of S100-A8 and S100-A9 proteins and is also critical for immune responses. S100-A9 is a cytoplasmic and secreted protein predominantly expressed in myeloid cells as well as neutrophils and monocytes but not expressed in lymphocytes. S100-A9 is found in high concentrations at sites of inflammation or in the serum of patients with inflammatory diseases. S100-A9 is also a cancer marker as it is up regulated in many cancers including gastric, esophageal, colon, breast and many more.
      References
      Product Information
      FormatPurified
      PresentationPurified rat monoclonal IgG1 in buffer containing PBS without preservatives.
      Quality LevelMQ100
      Applications
      ApplicationAnti-S100A9 Antibody, clone 2A5 (Azide Free) is an antibody against S100A9 for use in western blotting & activity assay.
      Key Applications
      • Western Blotting
      • Activity Assay
      Application NotesActivity Assay Analysis: A representative lot detected S100A9 and found that it increases neutrophil migration & induces the secretion of cytokines by monocytes (Cesaro, A., et al. (2012). PLOS ONE. 7(9):e45478 1-12).
      Western Blotting Analysis: A representative lot detected S100A9 in mouse neutrophils and recombinant mS100A9 (Cesaro, A., et al. (2012). PLOS ONE. 7(9):e45478 1-12).
      Biological Information
      ImmunogenRecombinant protein corresponding to mouse S100A9.
      Clone2A5
      Concentration1 mg/mL
      HostRat
      IsotypeIgG1
      Species Reactivity
      • Human
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • S100a9
      • Cagb
      • Mrp14
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~15 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Raji cell lysate.

      Western Blotting Analysis: 2.0 µg/mL of this antibody detected S100A9 in 10 µg of Raji cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABF290 04053252975677

      Documentation

      Anti-S100A9 Antibody, clone 2A5 (Azide Free) SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-S100A9 Antibody, clone 2A5 (Azide Free) Certificates of Analysis

      TitleLot Number
      Anti-S100A9, clone 2A5 (Azide Free) - Q2426886 Q2426886
      Anti-S100A9, clone 2A5 (Azide Free) - 3384392 3384392
      Anti-S100A9, clone 2A5 (Azide Free) - 3598001 3598001
      Anti-S100A9, clone 2A5 (Azide Free) - 3707325 3707325
      Anti-S100A9, clone 2A5 (Azide Free) - 3949757 3949757
      Anti-S100A9, clone 2A5 (Azide Free) Monoclonal Antibody 3126686

      References

      Reference overviewPub Med ID
      An inflammation loop orchestrated by S100A9 and calprotectin is critical for development of arthritis.
      Cesaro, Annabelle, et al.
      PLoS ONE, 7: e45478 (2012)  2012

      Show Abstract       		23029038 23029038