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MABF269 Anti-BTLA/cd272 Antibody, clone FLO67B

Anti-BTLA/cd272 Antibody, clone FLO67B is an antibody against BTLA/cd272 for use in Immunohistochemistry.

Anti-BTLA/cd272 Antibody, clone FLO67B MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: BTLA UniProt Number: Q7Z6A9
MABF269
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABF269
      DescriptionAnti-BTLA/cd272 Antibody, clone FLO67B
      Alternate Names
      • BTLA
      • CD272
      • B- and T-lymphocyte attenuator
      • B- and T-lymphocyte-associated protein
      Background InformationThe BTLA gene product B- and T-lymphocyte attenuator, also known as cluster of differentiation 272 (CD272), is a T cell coinhibitory receptor of the immunoglobulin superfamily with structural similarity to programmed cell death 1 (PD1) and CTLA4. BTLA is reported to negatively regulate immune responses via interaction with the B7 superfamily costimulatory molecule B7-H4 as well as with tumor necrosis factor receptor superfamily member 14 (TNFRSF14), also known as herpes virus entry mediator (HVEM). Polymorphisms in the BTLA gene have been associated with an increased risk of rheumatoid arthritis.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1λ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-BTLA/cd272 Antibody, clone FLO67B is an antibody against BTLA/cd272 for use in Immunohistochemistry.
      Key Applications
      • Immunohistochemistry
      Biological Information
      ImmunogenRecombinant protein corresponding to human BTLA/cd272.
      CloneFLO67B
      Concentration1 mg/mL
      HostMouse
      IsotypeIgG1λ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • BTLA
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight33 kDa calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunohistochemistry in human tonsil tissue.

      Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected BTLA/cd272 in human tonsil tissue (Dr. Giovanna Roncador, CNIO, Spain).
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABF269 04055977137163