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MABE902 Anti-Pax-2 Antibody, clone 4C2.2

This Anti-Pax-2 Antibody, clone 4C2.2 is validated for use in Western Blotting for the detection of Pax-2 .

Anti-Pax-2 Antibody, clone 4C2.2 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Nuclear Receptors Gene Symbol: PAX2 UniProt Number: Q02962
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MABE902
200 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBMCulture SupernatantMonoclonal Antibody
      Description
      Catalogue NumberMABE902
      DescriptionAnti-Pax-2 Antibody, clone 4C2.2
      Alternate Names
      • Paired box protein Pax-2
      • Pax-2
      Background InformationPaired box protein Pax-2 (UniProt Q02962; also known as Paired box homeotic gene 2) is encoded by the PAX2 (also known as FSGS7, PAPRS) gene (Gene ID 5076) in human. Pax-2 belongs to the family of transcription factors with conserved DNA-binding paired box domain. The family of paired box (PAX) genes is divided into four subgroups (I–IV). Genes in subgroups II (PAX2, PAX5, and PAX8) and III (PAX3 and PAX7) have been implicated in tumor development. PAX2 is a critical regulator of embryogenesis and it is normally expressed in the pancreas and in subpopulations of nodal lymphocytes in adult tissues. Aberrant PAX2 expression is frequently observed in several cancer types.
      References
      Product Information
      FormatCulture Supernatant
      PresentationMouse monoclonal IgG2bκ antibody in buffer containing supernatant without preservatives.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Pax-2 Antibody, clone 4C2.2 is validated for use in Western Blotting for the detection of Pax-2 .
      Key Applications
      • Western Blotting
      Application NotesWestern Blotting Analysis: A 1:500 dilution from a representative lot detected PAX-2 in 10 µg of HeLa and PC3 cell lysate.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human Pax-2.
      Clone4C2.2
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      SpecificityClone 4C2.2 is expected to react with spliced Pax-2 isoform 1 and isoform 2 (Fetal kidney isoform). Reactivity toward isoforms 3&4 has not been tested.
      IsotypeIgG2bκ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PAX2
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~45 kDa observed. ~45 kDa observed. Isoform 1 (44.7 kDa calculated); Isoform 2 (44.5 kDa calculated). An uncharacterized band ~17 kDa is seen in some lysate samples.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in A431 cell lysate.

      Western Blotting Analysis: A 1:500 dilution of this antibody detected PAX-2 in 10 µg of A431 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size200 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABE902 04055977175363