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ABT268 Anti-Liprin Alpha 1

This rabbit polyclonal Anti-Liprin Alpha 1, Cat. No. ABT268 detects Liprin alpha 1 in human cells. It has been tested for use in Western Blotting.

Anti-Liprin Alpha 1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Gene Symbol: PPFIA1, LIP1 UniProt Number: Q13136
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ABT268
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT268
      DescriptionAnti-Liprin Alpha 1
      Alternate Names
      • LAR-interacting protein 1
      • LIP-1
      • Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1
      • PTPRF-interacting protein alpha-1
      Background InformationLiprin-alpha-1 (UniProt: Q13136; also known as LAR-interacting protein 1, LIP-1, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1, PTPRF-interacting protein alpha-1) is encoded by the PPFIA1 (also known as LIP1) gene (Gene ID: 8500) in human. Liprin-alpha-1 is a member of the LAR (leukocyte common antigen-related) protein tyrosine phosphatase-interacting protein (liprin) family. It is a cytoplasmic protein that regulates the disassembly of focal adhesions. It forms homodimers and heterodimers with Liprin-alpha and Liprin-beta. Liprins contain an N-terminal coiled-coil domain and a C-terminal liprin homology (LH) region comprised of three sterile alpha motif (SAM) domains. The N-terminal region acts as a binding region for several synaptic proteins. SAM domain are known to bind to both protein kinases and phosphatases. In mast cells, liprin-alpha-1 facilitates exocytosis and cell spreading.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis rabbit polyclonal Anti-Liprin Alpha 1, Cat. No. ABT268 detects Liprin alpha 1 in human cells. It has been tested for use in Western Blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenGST-tagged recombinant fragment of 179 amino acids from the internal region of human Liprin Alpha 1.
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityThis polyclonal antibody detects Liprin Alpha 1 in human. It targets an epitope within 179 amino acids from the internal region of isoform 1 and 2.
      Species Reactivity
      • Human
      Species Reactivity NoteHuman.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PPFIA1
      • LIP1
      Purification MethodAffinity Purified
      UniProt Number
      Molecular Weight~160 kDa observed; 135.78 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HeLa cell lysate.

      Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Liprin Alpha 1 in 10 µg of HeLa cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABT268 04054839199349