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ABS811 Anti-FABP7 Antibody

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ABS811
100 μg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABS811
      ReplacesMABS184
      DescriptionAnti-FABP7 Antibody
      Alternate Names
      • Fatty acid-binding protein
      • brain
      • Brain lipid-binding protein
      • BLBP
      • Brain-type fatty acid-binding protein
      • B-FABP
      • Fatty acid-binding protein 7
      • Mammary-derived growth inhibitor related
      • FABP7
      Background InformationFABP7 is a member of the large family of hydrophobic ligand-binding proteins (FABPs). FABP proteins are involved in lipid metabolism, including uptake and intracellular trafficking of fatty acids and retinoids. In addition, they play a role in gene regulation, cell signaling, cell growth and differentiation. Several reports have suggested a possible role for the different FABP proteins in cancer biology, linking their levels with either increasing or decreasing the degree of malignancy. Nine FABPs (FABP1-FABP9) have been identified. FABP7 is a brain-specific protein that is required for the establishment of the radial glial fiber system in the developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers. It is expressed at high levels in the developing central nervous system. FABP7 has also been found in melanocytic lesions and has shown to regulate proliferation and invasion in melanoma cells in vitro, suggesting that it may play a role in cell proliferation and invasion.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-FABP7 Antibody is validated for use in Western Blotting_x000D_ and Immunohistochemistry for the detection of FABP7.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis (IHC): 5 μg/mL from a representative lot detected FABP7 in human breast tissue.

      Biological Information
      ImmunogenFABP7 antibody was raised against a 17 amino acid synthetic peptide from near the center of human FABP7.
      EpitopeNear Center
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • FABP7
      • BLBP
      • FABPB
      • MRG
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~24 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human breast tissue lysate.

      Western Blotting Analysis (WB): 1 μg/mL of this antibody detected FABP7 in human breast tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABS811 04055977174694

      Documentation

      Anti-FABP7 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-FABP7 Antibody Certificates of Analysis

      TitleLot Number
      Anti-FABP7 - VP1904036 VP1904036
      Anti-FABP7 -QVP1503132 QVP1503132
      Anti-FABP7 -VP1606162 VP1606162
      Anti-FABP7 -VP1609039 VP1609039
      Anti-FABP7 Polyclonal Antibody VP1808024

      Technical Info

      Title
      Characterization of Estrogen Receptor α Phosphorylation Sites in Breast Cancer Tissue Using the SNAP i.d® 2.0 System
      White Paper: Further considerations of antibody validation and usage.

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies