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ABN255 Anti-Bassoon Antibody

ABN255
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, H, RWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN255
      DescriptionAnti-Bassoon Antibody
      Alternate Names
      • Bassoon
      • Protein bassoon
      Background InformationProtein bassoon (also known as bassoon presynaptic cytomatrix protein, neuronal double zinc finger protein, zinc finger protein 231) is a cytoplasmic protein encoded by the BSN gene in human (also known as KIAA0434 and ZNF23118). Bassoon is found primarily in neurons in brain (PMID 9806829) and most likely functions as a scaffolding protein involved in organizing the presynaptic cytoskeleton. Murine and rodent orthologs are reported to be detected in axon terminals of hippocampal neurons, where it is highly concentrated in the vicinity of the active zone, indicating a potential involvement in cytomatrix organization at the site of neurotransmitter release (PMID 9679147).
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-Bassoon Antibody is an antibody against Bassoon for use in Western Blotting and Immunohistochemistry (Paraffin).
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Bassoon in rat cerebellum, human cerebral cortex, rat colon, mouse small intestine, and rat kidney tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to mouse Bassoon.
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityThis antibody is predicted to cross react with both isoforms.
      Species Reactivity
      • Mouse
      • Human
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Bsn
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~420 kDa observed. Uncharacterized band(s) may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse brain tissue lysate.

      Western Blotting Analysis: A 1:5,000 dilution of this antibody detected Bassoon in 10 µg of mouse brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN255 04055977158953