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ABF127 Anti-NKp30/CD337 Antibody

Anti-NKp30/CD337 Antibody is an antibody against NKp30/CD337 for use in Western Blotting, Immunohistochemistry .

Anti-NKp30/CD337 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: NCR3, 1C7, LY117 UniProt Number: O14931
ABF127
200 μg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABF127
      DescriptionAnti-NKp30/CD337 Antibody
      Alternate Names
      • NKp30/CD337
      • Natural cytotoxicity triggering receptor 3
      • Activating natural killer receptor p30
      • Natural killer cell p30-related protein
      • NK-p30
      • NKp30
      • CD337
      Background InformationNatural cytotoxicity triggering receptor 3 (UniProt O14931; also known as Activating NK-A1 receptor, Activating natural killer receptor p30, CD337, Lymphocyte antigen 117, Natural killer cell p30-related protein, NK-p30, NKp30) is encoded by the NCR3 (also known as 1C7, LY117, MALS) gene (Entrez Gene ID 259197) in human. NKp30/CD337 is a natural cytotoxicity receptor (NCR) that aids activated natural killer (NK) cells to mediate tumor cell lysis. NKp30 also helps eliminate immature DCs via BAG-6 (BCL2-associated athanogene 6 or Bat-3/Scythe) engagement, as well as by inducing TNF-alpha and IFN-gamma release from NK cells.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-NKp30/CD337 Antibody is an antibody against NKp30/CD337 for use in Western Blotting, Immunohistochemistry .
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected NKp30/CD337 in human spleen tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the extracellular domain of human NKp30/CD337.
      EpitopeExtracellular domain
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityReacts with all 6 human CD337 spliced isoforms (isoform 1/1C7a, isoform 2/1C7c, isoform 3/1C7b, isoform 4/1C7e, isoform 5/1C7f, isoform 6/1C7d).
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • NCR3
      • 1C7
      • LY117
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~33 kDa observed. The target band may appear as a smear ~35-45 kDa due to glycosylations and the presence of multiple isoforms.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in CD337 transfected HEK293 cell lysate.

      Western Blotting Analysis: 5.0 µg/mL of this antibody detected NKp30/CD337 in 10 µg of CD337 transfected HEK293 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size200 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABF127 04055977169089