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ABE1358 Anti-Zinc finger protein 593

Anti-Zinc finger protein 593 Antibody, Cat. No. ABE1358, is a highly specific rabbit polyclonal antibody that targets Zinc finger protein 593 and has been tested in Immunoprecipitation and Western Blotting.

Anti-Zinc finger protein 593 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Gene Symbol: ZNF593, ZT86 UniProt Number: O00488
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ABE1358
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MIP, WBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABE1358
      DescriptionAnti-Zinc finger protein 593
      Alternate Names
      • ZFP593
      • Zinc finger protein T86
      Background InformationZinc finger protein 593 (UniProt: O00488; also known as Zinc finger protein T86) is encoded by the ZNF593 (also known as ZT86) gene (Gene ID: 51042) in human. Zinc fingers are small protein domains wherein zinc plays a structural role contributing to the stability of the domain. Proteins containing zinc fingers are structurally diverse and perform a broad range of functions, including DNA replication and repair, transcription and translation, metabolism, cell proliferation, and apoptosis. Zinc finger domain 593 (ZNF593) belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family and contains a single C2H2 type zinc finger (amino acids 61-85). ZFP593 is largely disordered, with the exception of the zinc finger domain. It displays ubiquitous distribution and has been detected in spleen, prostate, testis, small intestine, and colon and in lower levels in thymus and peripheral blood leukocytes. ZFP593 is shown to negatively modulate the DNA binding activity of Oct-2. It can act either by binding to DNA octamer or by interacting with Oct-2. (Ref.: Srikrishna, S., et al. (2003), Nucleic Acid Res. 31(2): 532-550).
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Zinc finger protein 593 Antibody, Cat. No. ABE1358, is a highly specific rabbit polyclonal antibody that targets Zinc finger protein 593 and has been tested in Immunoprecipitation and Western Blotting.
      Key Applications
      • Immunoprecipitation
      • Western Blotting
      Application NotesWestern Blotting Analysis: A 1:500 dilution from a representative lot detected Zinc finger protein 593 in mouse embryonic stem cells. (Courtesy of Dr Adrian Bracken from Trinity College, Dublin).

      Immunoprecipitation Analysis: 2 ug from a representative lot detected Zinc finger protein 593 in mouse embryonic stem cells. (Courtesy of Dr Adrian Bracken from Trinity College, Dublin).
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to 14 amino acids from the C-terminal end of human Zinc finger protein 593.
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityThis polyclonal antibody detects zinc finger protein 593 in murine embryonic stem cells. It targets an epitope of 14 amino acids from the C-terminus.
      Species Reactivity
      • Mouse
      Species Reactivity NoteMouse. Predicted to react with Human, Bovine, Rhesus Macaque based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • ZNF593
      • ZT86
      Purification MethodAffinity Purified
      UniProt Number
      Molecular Weight~15 kDa observed. 15.20 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse embryonic stem cells.

      Western Blotting Analysis: A 1:500 dilution of this antibody detected Zinc finger protein 593 in 10 µg of mouse embryonic stem cells lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABE1358 04054839169588