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ABC1480 Anti-BCL6 Antibody

This Anti-BCL6 Antibody is validated for use in Western Blotting for the detection of BCL6.

Anti-BCL6 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: BCL6, BCL5, LAZ3, ZBTB27, ZNF51 UniProt Number: P41182
ABC1480
100 μg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      RWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC1480
      Replaces04-437
      DescriptionAnti-BCL6 Antibody
      Alternate Names
      • B-cell lymphoma 6 protein
      • BCL-6
      • B-cell lymphoma 5 protein
      • BCL-5
      • Protein LAZ-3
      • Zinc finger and BTB domain-containing protein 27
      • Zinc finger protein 51
      • BCL6
      Background InformationBCL6 Antibody: BCL6 was first identified as a proto-oncogene in diffuse large B cell lymphoma. BCL6, a transcriptional repressor, plays an important role in lymphomagenesis. It binds Stat recognition-like DNA elements and is required for affinity maturation of mature B cells in germinal centers and Th1/Th2 differentiation, a process that critically depends on BCL6-mediated transcriptional repression of p53. BCL6 is a pharmacological target for eradication of leukemia-initiating cells in chronic myeloid leukemia (CML).
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationThis Anti-BCL6 Antibody is validated for use in Western Blotting for the detection of BCL6.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenBCL6 antibody was raised against an 18 amino acid synthetic peptide near the center of human BCL6.
      EpitopeNear Center
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Rat
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • BCL6
      • BCL5
      • LAZ3
      • ZBTB27
      • ZNF51
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~68 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting/Peptide Inhibition Assay in rat lung tissue lysate.

      Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected BCL6 in 15 µg of rat lung tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABC1480 04055977174533